Nemex-2 Oral Liquid Dog Wormer 60 ml Pyrantel Pamoate

Description

Nemex-2
(pyrantel pamoate) Dewormer for dogs, 60ml. Effective against large roundworms and hookworms, two of the most common intestinal parasites in dogs. Caramel flavored, so most dogs love it. Administer 5ml per 10lbs of body weight orally. See label below for exact indications and recommendations. Nemex-2 has a wide safety margin and has been used safely and effectively for many years. Dating is December 2024. Thanks for looking and have a fine day.
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Nemex-2 Suspension
This treatment applies to the following species:
Dogs
Manufacturer: Zoetis
(pyrantel pamoate)
CANINE ANTHELMINTIC SUSPENSION
FOR ANIMAL USE ONLY
Description
Nemex-2 is a suspension of pyrantel pamoate in a palatable caramel-flavored vehicle. Each mL contains 4.54 mg of pyrantel base as pyrantel pamoate.
Pyrantel pamoate is a compound belonging to a family classified chemically as tetrahydropyrimidines. It is a yellow, water-insoluble crystalline salt of the tetrahydropyrimidine base and pamoic acid containing 34.7% base activity. The chemical structure and name are given below:
(
E
)-1,4,5,6-Tetrahydro-1-methyl-2-[2-(2-thienyl) vinyl] pyrimidine 4,4’ methylenebis [3-hydroxy-2-naphtoate] (1:1)
Nemex-2 Suspension Indications and Usage
Nemex-2 suspension is a highly palatable formulation intended as a single treatment for the removal of large roundworms
(Toxocara canis
and
Toxascaris leonina)
and hookworms
(Ancylostoma caninum
and
Uncinaria stenocephala)
in dogs and puppies. The presence of these parasites should be confirmed by laboratory fecal exam. Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism.
Nemex-2 suspension may also be used to prevent reinfestation of
T. canis
in puppies and adult dogs and in lactating bitches after whelping.
Precautions
THIS PRODUCT IS A SUSPENSION AND AS SUCH WILL SEPARATE. TO INSURE UNIFORM RESUSPENSION AND TO ACHIEVE PROPER DOSAGE,
IT IS EXTREMELY IMPORTANT THAT THE PRODUCT BE SHAKEN THOROUGHLY BEFORE EVERY USE
.
KEEP OUT OF REACH OF CHILDREN
Dosage and Administration
Administer 1 teaspoon (5 mL) for each 10 lb of body weight. It is not necessary to withhold food prior to or after treatment. Dogs usually find this dewormer very palatable and will lick the dose from the bowl willingly. If there is reluctance to accept the dose, mix in a small quantity of dog food to encourage consumption. It is recommended that dogs maintained under conditions of constant exposure to worm infestation should have a follow-up fecal exam within 2-4 weeks after treatment.
For maximum control and prevention of reinfestation, it is recommended that puppies be treated at 2, 3, 4, 6, 8, and 10 weeks of age. Lactating bitches should be treated 2-3 weeks after whelping. Adult dogs kept in heavily contaminated quarters may be treated at monthly intervals to prevent
T. canis
reinfestation.
SAFETY AND EFFICACY STUDIES:
Critical (worm count) studies in dogs demonstrated that Nemex-2 at the recommended dosage is highly efficacious against
T. leonina
(99%),
T. canis
(85%),
A. caninum
(97%), and
U. stenocephala
(94%).
One of the most outstanding and significant features of Nemex-2 is its wide margin of therapeutic safety in dogs. The acute oral LD
50
of pyrantel pamoate administered in gelatin capsules to female and male dogs is greater than 314 mg base per lb of body weight, which indicates a therapeutic index in excess of 138 times the recommended dosage. In subacute and chronic studies, no significant morphological abnormalities could be attributed to Nemex-2 when administered to dogs at daily dose rates up to 94 mg base per lb of body weight (40x) for periods of 19, 30, and 90 days. Clinical studies conducted in a wide variety of geographic locations using more than 40 different breeds of dogs showed no drug-induced toxic effects. Included in these studies were nursing pups, weaned pups, adults, pregnant bitches, and males at stud. Additional data have demonstrated the safe use of Nemex-2 in dogs having heartworm infestations and/or receiving medication for heartworms, dogs exposed to organophosphate flea collars or flea/tick dip treatments, and dogs undergoing concurrent treatment or medication at the time of worming such as immunization and antibacterial treatment.
RECOMMENDED STORAGE:
Store below 30°C (86°F).
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